In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper for effector translocation
Yue, J.*, Heydari S.*, Park D., Chetrit D., Tachiyama S., Guo W., Botting J.M., Wu S., Roy C.R.#, Liu J.# bioRxiv (2025)
Structure and infection dynamics of mycobacteriophage Bxb1
Freeman, K.G., Mondal, S., Macale, L.S., Podgorski, J., White, S.J., Silva, B.H., Ortiz, V., Huet, A., Perez, R.J., Narsico, J.T., Ho, M., Jacobs-Sera, D., Lowary, T.L., Conway, J.F., Park, D.#, and Hatfull, G.F.#. Cell (2025)
https://www.cell.com/action/showPdf?pii=S0092-8674%2825%2900345-9
https://www.scripps.edu/news-and-events/press-room/2025/20250415-park-phage-therapies.html
Cellular function of a biomolecular condensate is determined by its ultrastructure
Scholl, D., Boyd, T., Latham, A.P., Salazar, A., Khan, A., Boeynaems, S., Holehouse, A.S., Lander, G.C., Sali, A., Park, D.#, Deniz, A.A.#, and Lasker, K.#. Pre-print (2024)
Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor cancer therapy
SL Klupt*, KT Fam*, X Zhang, PK Chodisetti, A Mehmood, T Boyd, DA Grotjahn, D Park, HC Hang. Elife (2024)
Reentrant DNA shells tune polyphosphate condensate size
R Chawla*, JKA Tom*,T Boyd, NH Tu, T Bai, DA Grotjahn, D Park, AA Deniz, LR Racki. Nature Communications (2024)
The Parkinson's disease kinase LRRK2 coordinates a cell intrinsic itaconate-dependent defense pathway against the intracellular pathogen Salmonella
H Lian*, D Park*, M Chen, F Schueder, M Lara-Tejero, J Liu, JE Galan. Nature Microbiology (2023)
Developmental transitions coordinate assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System
D Park, S Steiner, M Shao, CR Roy, J Liu. Infection & Immunity (2022)
In-situ high-resolution 3D imaging combined with proteomics and metabolomics reveals enlargement of subcellular architecture and enhancement of photosynthesis pathways in nuclear-irradiated Chlorella pyrenoidosa.
W Guo, L Feng, Z Wang, J Guo, D Park, BL Carroll, X Zhang, J Liu, J Cheng. Chemical Engineering Journal (2022)
https://www.sciencedirect.com/science/article/abs/pii/S1385894721046131
Analysis of Dot/icm type IVB secretion system subassemblies by cryoelectron tomography reveals conformational changes induced by DotB binding
D Park*, D Chetrit*, B Hu, CR Roy, J Liu. Mbio (2020)
A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography
X Li, D Park, Y Chang, A Radhakrishnan, H Wu, P Wang, J Liu. Progress in Biophysics and Molecular Biology (2020)
https://www.sciencedirect.com/science/article/abs/pii/S0079610720300924?via%3Dihub
Applying live cell imaging and cryo-electron tomography to resolve spatiotemporal features of the Legionella pneumophila Dot/Icm secretion system
D Chetrit, D Park, B Hu, J Liu, CR Roy. JoVE (2020)
Cryo-electron microscopy visualization of a large insertion in the 5S ribosomal RNA of the extremely halophilic archaeon Halococcus morrhuae
MR Tirumalai, JT Kaelber, DR Park, Q Tran, GE Fox. FEBS Open Bio (2020)
https://febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.12962
Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography
D Park, M Lara-Tejero, MN Waxham, W Li, B Hu, JE Galán, J Liu. Elife (2018)
Structural basis for membrane anchoring of HIV-1 envelop spike
J Dev*, D Park*, Q Fu, J Chen, H Ha, F Ghantous, T Herrmann, W Chang, Z Liu, G Frey, MS Seaman, B Chen, JJ Chou. Science (2016)
Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein
J Chen, JM Kovacs, H Peng, S Rits-Volloch, J Lu, D Park, El Zablowsky, MS Seaman, B Chen. Science (2015)