Selected publications
Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure.
Scholl, D., Boyd, T., Latham, A.P., Salazar, A., Khan, A., Boeynaems, S., Holehouse, A.S., Lander, G.C., Sali, A., Park, D.#, Deniz, A.A.#, and Lasker, K.# (2024)
https://www.biorxiv.org/content/10.1101/2024.12.27.630454v1
# corresponding
Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor cancer therapy
SL Klupt*, KT Fam*, X Zhang, PK Chodisetti, A Mehmood, T Boyd, DA Grotjahn, D Park, HC Hang. Elife (2024)
https://elifesciences.org/articles/95297
https://www.biorxiv.org/content/10.1101/2023.11.19.567738v1
*Equal contribution
Reentrant DNA shells tune polyphosphate condensate size
R Chawla*, JKA Tom*,T Boyd, NH Tu, T Bai, DA Grotjahn, D Park, AA Deniz, LR Racki. Nature Communications (2024)
https://www.nature.com/articles/s41467-024-53469-x
https://www.biorxiv.org/content/10.1101/2023.09.13.557044v1
*Equal contribution
The Parkinson's disease kinase LRRK2 coordinates a cell intrinsic itaconate-dependent defense pathway against the intracellular pathogen Salmonella
H Lian*, D Park*, M Chen, F Schueder, M Lara-Tejero, J Liu, JE Galan. Nature Microbiology (2023)
https://www.nature.com/articles/s41564-023-01459-y#Sec41
*Equal contribution
Developmental transitions coordinate assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System
D Park, S Steiner, M Shao, CR Roy, J Liu. Infection & Immunity (2022)
https://journals.asm.org/doi/10.1128/iai.00410-22
Analysis of Dot/icm type IVB secretion system subassemblies by cryoelectron tomography reveals conformational changes induced by DotB binding
D Park*, D Chetrit*, B Hu, CR Roy, J Liu. Mbio (2020)
https://journals.asm.org/doi/full/10.1128/mBio.03328-19
*Equal contribution
Visualization of the type III secretion mediated Salmonella-host cell interface using cryo-electron tomography
D Park, M Lara-Tejero, MN Waxham, W Li, B Hu, JE Galán, J Liu. Elife (2018)
Structural basis for membrane anchoring of HIV-1 envelop spike
J Dev*, D Park*, Q Fu, J Chen, H Ha, F Ghantous, T Herrmann, W Chang, Z Liu, G Frey, MS Seaman, B Chen, JJ Chou. Science (2016)
https://www.science.org/doi/full/10.1126/science.aaf7066
*Equal contribution
Additional publications
Effect of the cytoplasmic domain on antigenic characteristics of HIV-1 envelope glycoprotein
J Chen, JM Kovacs, H Peng, S Rits-Volloch, J Lu, D Park, El Zablowsky, MS Seaman, B Chen. Science (2015)
A mammalian system for high-resolution imaging of intact cells by cryo-electron tomography
X Li, D Park, Y Chang, A Radhakrishnan, H Wu, P Wang, J Liu. Progress in Biophysics and Molecular Biology (2020)
Cryo-electron microscopy visualization of a large insertion in the 5S ribosomal RNA of the extremely halophilic archaeon Halococcus morrhuae
MR Tirumalai, JT Kaelber, DR Park, Q Tran, GE Fox. FEBS Open Bio (2020)
Applying live cell imaging and cryo-electron tomography to resolve spatiotemporal features of the Legionella pneumophila Dot/Icm secretion system
D Chetrit, D Park, B Hu, J Liu, CR Roy. JoVE (2020)
In-situ high-resolution 3D imaging combined with proteomics and metabolomics reveals enlargement of subcellular architecture and enhancement of photosynthesis pathways in nuclear-irradiated Chlorella pyrenoidosa.
W Guo, L Feng, Z Wang, J Guo, D Park, BL Carroll, X Zhang, J Liu, J Cheng. Chemical Engineering Journal (2022)